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phenobarbital will decrease the extent or outcome of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Potent or average CYP3A4 inducers may perhaps maximize level of diazepam elimination; hence, efficacy of diazepam may be lessened.Hypnotic doses of barbiturates will not seem to impair uterine action